The Extract Factory is a specialized manufacturer and bulk supplier of botanical actives for the global nutraceutical, dietary supplement, and functional food industries. Our Andrographis Paniculata Extract Powder is standardized to precise Andrographolide concentrations ranging from 10% to 98%, delivering the batch-to-batch consistency, full traceability, and documented quality that formulators, contract manufacturers, and international distributors require for immune-health and anti-inflammatory product lines.
Botanical Source & Traceability
We exclusively utilize the whole aerial part—leaves and stems—of Andrographis paniculata, commonly known as Kalmegh or King of Bitters. Raw materials are procured from qualified agricultural partners and subjected to strict incoming inspection for identity, purity, and environmental contaminants. Selecting the aerial portion is a deliberate quality strategy: it naturally concentrates the desired actives while minimizing the heavy metal accumulation often associated with root biomass. The leaves and stems typically contain approximately 0.6% andrographolide, providing a favorable raw-material yield that supports cost-efficient, standardized extraction without compromising marker potency.
Extraction & Manufacturing Excellence
Our production protocol adheres to documented standard operating procedures (SOPs) through every process stage, from washing, drying, and comminution to solvent extraction, concentration, purification, and low-temperature spray drying. To protect product integrity, we maintain a dedicated, targeted production line for our 98% Andrographolide powder. Physical segregation prevents cross-contamination with other botanical extracts, ensuring supply stability, reduced allergen risk, and absolute batch integrity for high-purity applications.
Standardized Andrographolide Grades
We offer four primary specification tiers engineered for distinct dosage forms and market positioning:
10% Andrographolide
A lower-concentration, entry-level grade presenting as a light yellow to cream-colored powder. Ideal for introductory immune-modulation, anti-inflammatory, and digestive-support supplements.30% Andrographolide
A moderate-concentration grade with a light brown to pale yellow appearance. Suitable for general-use immune enhancement, respiratory support, and antimicrobial formulations requiring a higher active loading than entry-level grades.50% Andrographolide
A professional-use, higher-concentration grade with a dark brown color profile. Targeted at inflammation-control, advanced immune modulation, and antioxidant complexes where maximum potency from a natural matrix is desired.98% Andrographolide
An ultra-high-purity, off-white fine powder optimized for antiviral research, anti-tumor studies, and premium pharmaceutical or clinical-nutrition applications requiring maximized purity and efficacy.
Physical & Analytical Profile
Physical Properties
- Appearance: Ranges from light yellow/cream (10%) to dark brown (50%); the 98% grade is an off-white to white fine powder. Conforms to visual inspection.
- Odor: Characteristic aroma of Andrographis paniculata; conforms to organoleptic analysis.
- Taste: Characteristic taste profile; conforms to organoleptic evaluation.
- Bulk Density: 0.52 g/ml (USP 616).
- Particle Size: 95% through 80 Mesh (CP2015).
Chemical Analysis
- Andrographolide: ≥98% — Actual: 98.21% (HPLC).
- Moisture: ≤1% — Actual: 0.21% (CP2015, 105°C, 4 h).
- Ash: ≤1% — Actual: 0.15% (CP2015).
- Total Heavy Metals: <10 ppm (Conforms, CP2015).
Microbiological Control
- Aerobic Bacterial Count: ≤1,000 CFU/g — Conforms (GB4789.2).
- Yeast: ≤100 CFU/g — Conforms (GB4789.15).
- Mold: ≤100 CFU/g — Conforms (GB4789.15).
- Escherichia coli: <3.0 MPN/g — Conforms (GB4789.38).
- Salmonella: Not Detected — Conforms (GB4789.4).
- Staphylococcus aureus: Not Detected — Conforms (GB4789.10).
Solubility, Stability & Formulation Compatibility
Andrographolide is a diterpenoid lactone characterized by limited aqueous solubility and high solubility in ethanol and methanol. For dietary supplement applications, the extract is highly compatible with hard-shell encapsulation, tablet compression, and lipid-based delivery systems; lower-concentration grades also blend well into functional beverage bases and powdered drink mixes when properly suspended or emulsified.
Stability studies conducted under varied storage conditions confirm that the product retains its active marker concentration throughout the intended shelf life when stored in a tightly sealed container, protected from light, moisture, and oxygen. We recommend warehouse storage below 25°C with relative humidity below 60%.
Quality Assurance & Testing Infrastructure
Every production lot is screened in-house using high-performance liquid chromatography (HPLC) for quantitative active assay, gas chromatography (GC) for residual solvent verification, and UV spectrophotometry for identity confirmation. Our heavy metal screening covers lead, mercury, and cadmium to ensure results remain within safe, compliance-grade limits. All microbiological assays are executed against GB and CP2015 methodologies. For clients requiring additional documentation, we facilitate third-party testing through reputable institutions such as Eurofins.
Functional Profile & Mechanisms of Action
Andrographolide, the principal bioactive constituent of Andrographis paniculata extract powder, is extensively studied for its multi-targeted pharmacological activities. It demonstrates potent immunomodulatory effects by supporting cytokine balance and natural killer cell activity. As an anti-inflammatory agent, it is recognized for modulating the NF-κB signaling pathway, thereby helping regulate the body’s inflammatory response. The compound also exhibits significant antioxidant capacity by scavenging reactive oxygen species and upregulating cellular antioxidant enzyme activity. Additionally, documented broad-spectrum antimicrobial properties make it valuable for formulations targeting bacterial, viral, and fungal challenges.
Industry Applications
Our Andrographis Paniculata Extract Powder is suited for a wide spectrum of B2B applications:
- Immune Support Supplements: Capsules, tablets, and sachets for daily defense and seasonal wellness.
- Respiratory Health Formulas: Synergistic blends targeting airway comfort and upper-respiratory integrity.
- Anti-Inflammatory Complexes: Combination products with turmeric, boswellia, or ginger for joint and muscle support.
- Digestive Health Lines: Traditional gastrointestinal comfort formulations leveraging Kalmegh’s bitter principles.
- Pharmaceutical Research: High-purity 98% Andrographolide for antiviral, oncology, and immunology R&D pipelines.
Packaging, Storage & Shelf Life
The Extract Factory supplies this ingredient in customizable wholesale packaging, from 1 kg vacuum-sealed aluminum foil bags to 25 kg food-grade fiber drums with double-layer polyethylene liners. All packaging is designed to prevent moisture ingress and preserve organoleptic stability during international transit. Store in a cool, dry place away from direct sunlight and strong odors.
Why Partner with The Extract Factory
- Yield-Optimized Sourcing: By leveraging the ~0.6% natural andrographolide content present in the leaves and stems, we maximize extraction efficiency and pass those economies on to our partners as highly cost-effective bulk pricing.
- Dedicated High-Purity Lines: Our 98% Andrographolide is produced on segregated equipment, eliminating cross-contamination risks and ensuring long-term supply continuity.
- Custom Specification Capability: We routinely customize extract ratios, particle-size distributions, and carrier systems to align with your finished-product specifications.
- Scalable Volume Programs: Whether you require an initial development batch or multi-ton annual volumes, our pricing structure includes competitive wholesale rates and incremental volume discounts for large-scale procurement.
Contact Us
For technical data sheets, samples, or a detailed quotation on Andrographis Paniculata Extract Powder, please contact our sales and technical team directly.
Email: [email protected]
